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Molecular biology software SnapGene 8.0.0: a major update with new features and numerous bug fixes

SnapGene 8.0 brings a new look and feel to the main data viewer, new features for batch annotation and data usage, and new ways to edit alignments to reference sequences.
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Feature highlights

1. Batch annotation of plasmid features and primers

Quickly detect common features and add primer lists to multiple sequences selected in the project folder panel, change sequence properties such as methylation and topology, and easily align and gel simulate selected sequences.

2. Modern, simplified map, sequence, feature, and primer views

Updated map, sequence, feature, and primer views have been restructured and simplified to highlight key data and features, and flexible filtering and sorting capabilities have been added to the feature and primer tables.

3. Edit alignments to reference DNA sequences

When using the “Align to Reference DNA Sequence” feature, you can now confidently verify your sequence by editing the gap positions in Sanger sequencing traces and virtual builds.

4. Enhanced file and folder interaction

Data management has been simplified with improved file selection in the folder panel and new visualization and usage of unsaved files.

Detailed changes

1. Enhanced annotation and conversion capabilities for multiple files in a project

– Import features or detect common features in multiple DNA files.

– Import primers to multiple sequences from a list or SnapGene, VNTI, or Clone Manager files.

– Circularize, linearize, or flip multiple nucleotide files.

– Change file properties for multiple sequences, including methylation, topology, and strand directionality.

– Select enzymes to display for multiple DNA files.

– Edit DNA or RNA ends for multiple sequences.

– Generate DNA, RNA, or protein for multiple sequences.

– Clean up history in multiple files.

2. Enhanced file management capabilities in a project

– Added the ability to select folders and display prompts for partial folder selections.

– Quickly clear the entire selection or deselect files by type.

– Deselect files of other types by holding down the Option/Alt key and clicking the X to the right of the file count for a given file type.

– File/folder selection is cleared when closing the last tab in the project window.

– Added help links.

– Improved visualization and use of unsaved changes. A yellow dot is displayed next to files in the folder panel and tabs, and a warning is displayed at the top of the project folder tree. Added options to “Save All”, “Discard All”, or “Select Unsaved Files” in the project.